Seattle is known for its rain, but in actuality, it doesn't actually rain that much. Visiting in the summer months will yield you the best weather and the most sun, though.
Staying in Downtown Seattle or Belltown will be the most convenient, putting you close to the top sights on your 2 days in Seattle itinerary, and near transit.
Start your day at Olympic Sculpture Park then exploring the waterfront. Then, spend a few hours at Pike Place Market, sampling all of the food offerings.
Explore the Pioneer Square neighborhood, home to the Underground Tour and historic Smith Tower. End day 1 of your Seattle itinerary with dinner and drinks in Capitol HIll.
Check out all the attractions in the Seattle Center- go to the top of the Space Needle, admire the glass art at Chihuly Garden & Glass, and learn about pop culture at MoPOP.
Say hi to the Fremont Troll, explore Gas Works Park, and check out the breweries of Ballard. End your 2 days in Seattle itinerary with dinner and drinks in Belltown.